Preservation of biospecimens at ambient temperature: special focus on nucleic acids and opportunities for the biobanking community

Biopreservation and Biobanking Vol. 14, No. 2
Muller R, Betsou F, Barnes MG, Harding K, Bonnet J, Kofanova O, Crowe JH; International Society for Biological and Environmental Repositories (ISBER) Biospecimen Science Working Group.
https://www.liebertpub.com/doi/abs/10.1089/bio.2015.0022
Several approaches to the preservation of biological materials at ambient temperature and the relative impact on sample stability and degradation are reviewed, with a …Lire la suite

A novel method for room temperature distribution and conservation of RNA and DNA reference materials for guaranteeing performance of molecular diagnostics in onco-hematology: A GBMHM study

Clinical Biochemistry Volume 48, Issue 15, October 2015, Pages 982-987
Jean-Michel Cayuela, Carole Mauté, Anne-Lise Fabre, Olivier Nibourel, Stéphanie Dulucq, Eric Delabesse, Patrick Villarèse, Sandrine Hayette, Marie-Joelle Mozziconacci, Elizabeth Macintyre, on behalf of GBMHM
https://www.sciencedirect.com/science/article/pii/S0009912015001289
Objectives
Performance of methods used for molecular diagnostics must be closely controlled by regular analysis of internal quality controls. However, conditioning, shipping and long …Lire la suite

La dégradation et la réparation de l’ADN, Lindahl, Arrhenius et Imagene

Le prix Nobel de chimie 2015 récompense des travaux sur la dégradation spontanée de l’ADN, dégradation spontanée dont l’étude a conduit à la validation de la technologie Imagene.
L’attribution du prix Nobel de chimie reconnaissant la contribution de trois chercheurs au domaine  de la réparation de l’ADN est importante pour qui s’intéresse à la stabilité -et …Lire la suite